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Lab alumnus entering dental school at Case Western Reserve University

Zack Haley

Long-time lab member Zack Haley recently graduated from Ashland University and will be entering the Case Western Reserve University School of Dental Medicine this Fall.  Zack started working in our lab during his sophomore year and took the lead on our current project characterizing how mammals and zebrafish regulate the expression of alpha crystallins, proteins involved in protecting cells from damage during physiological stress.

During his time in our lab Zack presented his research at a meeting of the Ohio Academy of Sciences and at two undergraduate research symposia at Ashland.  He was a co-author on a poster I presented at last month’s Seattle meeting of the Association for Research in Vision and Ophthalmology.  Check back soon for some news about the trip to Seattle.  In the meantime, the zebrafish embryo below is data from our poster showing green fluorescent protein expressed under the control of a promoter for mouse alpha B-crystallin.  This result shows that zebrafish cells are able to “read” this mouse DNA sequence and direct the expression of the gene under its control.

GFP protein expression driven in the zebrafish notochord by a mouse alpha B-crystallin promoter

GFP protein expression driven in the zebrafish notochord by a mouse alpha B-crystallin promoter.

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