Over the last three years my lab has been using the zebrafish as a model for studying the effects of a diverse group of lens proteins called crystallins on lens development. You can read more about the evolution of these lens proteins in a previous post. We just added a new tool to the lab for these studies – a Leica CM1850 Cryostat. This machine allows us to take thin sections through zebrafish larvae to identify any abnormal eye and lens development.
Jackie Skiba, an undergraduate research student in our lab, has been taking the new cryostat out for its shakedown run this summer: